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  1. The lumenal portion of PDI8 was able to functionally complement the loss of the prokaryotic protein foldase, disulfide oxidase (Dsb A), as demonstrated by the reconstitution of periplasmic alkaline phosphatase in The results indicate that PDI8 is a type I transmembrane protein with its catalytic domain facing the lumen of the ER and functions in the oxidation of cysteines to produce disulfide bonds.

  2. It's Just Lunch, a dating service for single professionals, surveyed single American adults and found that nearly 70 percent of men and about 50 percent of women won't bother with a second date if the chemistry isn't there. First, let's get you through the nerve-wracking first date.